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Finasteride is also used to treat male pattern baldness (androgenic alopecia) in men, a condition that develops in up to 80% of Caucasian men aged 70 and over. [ 24 ] [ 4 ] In the United States, finasteride and minoxidil are the only two FDA approved drugs for the treatment of male pattern hair loss as of 2017. [ 25 ]
A clinical study that compared the effects of oral finasteride against a finasteride 0.25% topical solution was carried out on 24 men with androgenetic alopecia.
[40] 5α-DHP is a major hormone in circulation of normal cycling and pregnant women. [ 41 ] Other enzymes compensate to a degree for the absent conversion of 5α-reductase, specifically with local expression at the skin of reductive 17β-hydroxysteroid dehydrogenase , and oxidative 3α-hydroxysteroid dehydrogenase and 3β-hydroxysteroid ...
Other 5α-reductase inhibitors such as finasteride (a type 2 inhibitor) have been used off-label to treat excessive hair growth in women with hirsutism. [3] [23] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism. However, dutasteride is not recommended for ...
For example, in clinical studies of finasteride for BPH, just over eight percent of men reported an effect on their erections, with 6.4 percent and 3.7 percent of men reporting decreases in libido ...
In comparison, the rate of improvement was 80.5 percent for men who used finasteride and just 59 percent for men who only used minoxidil. You may have heard of topical minoxidil under the brand ...
Finasteride is contraindicated in pregnancy.[36][37] The Food and Drug Administration advises that donation of blood or plasma be deferred for at least one month after taking the last dose of finasteride.[38] I suggest, based on Refs 36 and 37 (manufacturers' prescribing information as deposited with the FDA), that the above be altered to:
Research shows that taking 5 milligrams (mg) of finasteride a day for benign prostatic hyperplasia (BPH) — an enlarged prostate — can lead to a 15 to 25 percent increase in testosterone levels.