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Apitherapy is a branch of alternative medicine that uses honey bee products, including honey, pollen, propolis, royal jelly and bee venom. There has been no scientific or clinical evidence for the efficacy or safety of apitherapy treatments. [1] [2] Bee venom can cause minor or major reactions, including allergic responses, anaphylaxis or death.
Bee venom is also considered ineffective for the treatment or prevention of cancer, with no clinical studies to date supporting such effects. [10] According to the American Cancer Society , there is no scientific evidence that apitherapy or bee venom therapy can treat or change the course of cancer or any other disease. [ 11 ]
A male Xylocopa virginica (Eastern Carpenter bee) on Redbud (Cercis canadensis). Bees can suffer serious effects from toxic chemicals in their environments. These include various synthetic chemicals, particularly insecticides, as well as a variety of naturally occurring chemicals from plants, such as ethanol resulting from the fermentation of organic materials.
Chemotherapy for NSCLC usually includes combination of two drugs (chemotherapy doublet), with one of the agents is cisplatin or carboplatin. In 2002, Schiller at al. published in the New England Journal of Medicine, a study that compared four chemotherapy regimens for advanced NSCLC, cisplatin and paclitaxel, cisplatin and gemcitabine, cisplatin and docetaxel, and carboplatin and paclitaxel. [14]
Lung squamous-cell carcinoma is the second most common histologic type of lung cancer after adenocarcinoma, reaching 22.6% of all lung cancer cases as of 2012. [11] The relative incidence of the former has been steadily decreasing in favor of the latter due to the decreasing smoking rates in the last few years. [9]
Patients exposed to low doses of grayanotoxin typically recover within a few hours. In more severe cases, symptoms may persist for 24 hours or longer and may require medical treatment (as described above). Despite the risk from cardiac problems, grayanotoxin poisoning is rarely fatal in humans. [11]
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