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Clomifene was studied in the treatment of advanced breast cancer during the period of 1964 to 1974 and was found to be effective but was abandoned due to concerns about desmosterolosis with extended use. [44] [51] [52] Short-term use (e.g. days to months) did not raise the same concerns and clomifene continued to be studied for other ...
Clomiphene is initiated for use in patients with polycystic ovary syndrome, psychogenic amenorrhea, post-oral contraceptive amenorrhea, and secondary amenorrhea of unidentified cause. [14] Serum estrogen should be measured prior to therapy which rules out primary pituitary or ovarian failure , endometrial carcinoma , hyperprolactinaemia .
The best time to take metformin depends on the medication type and dosage. Some people take metformin once, twice or even three times a day, depending on the type of metformin (tablet or liquid ...
Clomifene citrate (Clomid is a common brand name) is the medication which is most commonly used to treat anovulation. It is a selective estrogen-receptor modulator, affecting the hypothalamic–pituitary–gonadal axis to respond as if there was an estrogen deficit in the body, in effect increasing the production of follicle-stimulating hormone.
Compared to them, the mortality rate was 4% higher for those who took multivitamins daily and 9% higher for those who took them less often. Younger vitamin users had the highest risk.
Clomiphene is a selective estrogen receptor modulator (SERM). [5] It is the most widely used fertility drug. [ 6 ] Other medications in this class include tamoxifen and raloxifene , although both are not as effective as clomiphene and are thus less widely used for fertility purposes. [ 7 ]
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Enclomifene (INN Tooltip International Nonproprietary Name), or enclomiphene (USAN Tooltip United States Adopted Name), a nonsteroidal selective estrogen receptor modulator of the triphenylethylene group, acts by antagonizing the estrogen receptor (ER) in the pituitary gland, which reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, thereby increasing gonadotropin ...