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Anencephaly is the absence of a major portion of the brain, skull, and scalp that occurs during embryonic development. [1] It is a cephalic disorder that results from a neural tube defect that occurs when the rostral (head) end of the neural tube fails to close, usually between the 23rd and 26th day following conception. [ 2 ]
The condition is frequently, though not always, associated with anencephaly. The fetus is said to have acrania if it meets the following criteria: the fetus should have a perfectly normal facial bone, a normal cervical column but without the fetal skull and a volume of brain tissue equivalent to at least one-third of the normal brain size. [2]
Neural tube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third week of pregnancy called gastrulation, specialized cells on the dorsal side of the embryo begin to change shape and form the neural tube.
A child must also exhibit four other symptoms in order to be clinically diagnosed. However, according to the Omnigraphics Health References Series: Depression Sourcebook, Third Edition, [35] a more calculated evaluation must be given by a medical or mental health professional such as a physiologist or psychiatrist. Following the bases of ...
The skull does not close all the way in this deformity (especially at the occipital region). As a result, the amniotic fluid enters the brain, leading to eventual brain degeneration and anencephaly. [1] Craniorachischisis is on the extreme end of the dysraphism spectrum, wherein the entire length of the neural tube fails to close. [2]
Exencephaly is a type of cephalic disorder wherein the brain is located outside of the skull. This condition is usually found in embryos as an early stage of anencephaly.As an exencephalic pregnancy progresses, the neural tissue gradually degenerates.
The Center for Epidemiologic Studies Depression Scale for Children (CES-DC) is a modified version of the Center for Epidemiologic Studies Depression Scale. This measure assesses both depressive symptoms as well as symptom improvement in a wide range of children and adolescents, ages 6–17. [ 3 ]
The Children's Depression Inventory (CDI and CDI2) is a psychological assessment that rates the severity of symptoms related to depression or dysthymic disorder in children and adolescents. [1] The CDI is a 27-item scale that is self-rated and symptom-oriented. [1] The assessment is now in its second edition.