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The ZMA formula is composed of zinc monomethionine aspartate (30 mg), magnesium aspartate (450 mg), and vitamin B 6 as pyridoxine hydrochloride (10.5 mg). The manufacturer recommends that ZMA be taken 30 – 60 minutes before bedtime with an empty stomach to help synchronize absorption with sleep.
Zinc picolinate (or ZnPic) is the zinc coordination complex derived from picolinic acid and zinc(II). It has the formula Zn(NC 5 H 4 CO 2 ) 2 (H 2 O) 2 . The complex adopts an octahedral molecular geometry , containing two bidentate picolinate ligands (conjugate base of picolinic acid) and two aquo ligands .
Structure of Zn(picolinate) 2 (H 2 O) 2. Hydrogenation of picolinic acid gives piperidine-2-carboxylic acid, a precursor to the drug Mepivacaine. Picolinic acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. [5] [6] It is a substrate in the Mitsunobu reaction.
Zinc toxicity is a medical condition involving an overdose on, or toxic overexposure to, zinc. Such toxicity levels have been seen to occur at ingestion of greater than 50 mg of zinc. [1] [unreliable medical source?] Excessive absorption of zinc can suppress copper and iron absorption. The free zinc ion in solution is highly toxic to bacteria ...
Zinc supplement is an effective treatment for acrodermatitis enteropathica, a genetic disorder affecting zinc absorption that was previously fatal to affected infants. [76] Zinc deficiency has been associated with major depressive disorder (MDD), and zinc supplements may be an effective treatment. [187] Zinc may help individuals sleep more. [10]
Zinc sulfate is used medically as a dietary supplement. [1] Specifically it is used to treat zinc deficiency and to prevent the condition in those at high risk. [1] This includes use together with oral rehydration therapy for children who have diarrhea. [2] General use is not recommended. [1] It may be taken by mouth or by injection into a vein ...
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