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A wide variety of deoxyribonucleases are known and fall into one of two families (DNase I or DNase II), which differ in their substrate specificities, chemical mechanisms, and biological functions. Laboratory applications of DNase include purifying proteins when extracted from prokaryotic organisms.
Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. [5] DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides.
He played a role in founding Venezuela's National Institute of Biomedicine and held many leprosy-related positions. Among Convit's many honors for his work on leprosy and tropical diseases was Spain's Prince of Asturias Award in the Scientific and Technical Research category and France's Legion of Honor .
The Centre of Biological Research (Spanish: Centro de Investigaciones Biológicas) is a leading research centre in Spain, specialising in molecular genetics. It belongs to the Spanish National Research Council (CSIC). Created in 1958, the centre leads Spanish and European research in the fields of biology and biomedicine.
The Institute for Research in Biomedicine (IRB Barcelona) [1] is an institution engaged in fundamental research at the interface between molecular and cell biology, computational and structural biology and chemistry, with experts in proteomics, genomics, biostatistics and advanced digital microscopy. The institute was created by the Government ...
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Pages in category "Deoxyribonucleases" The following 4 pages are in this category, out of 4 total. This list may not reflect recent changes. C. Cas9; E ...
Exodeoxyribonucleases are both exonucleases and deoxyribonucleases. They catalyze digestion of the ends of linear DNA. They are a type of esterase.