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2 consecutive measurements exceed 2 standard deviations of the reference range, and on the same side of the mean. Inaccuracy and/or imprecision R 4s: Two measurements in the same run have a 4 standard deviation difference (such as one exceeding 2 standard deviations above the mean, and another exceeding 2 standard deviations below the mean).
If a data distribution is approximately normal then about 68 percent of the data values are within one standard deviation of the mean (mathematically, μ ± σ, where μ is the arithmetic mean), about 95 percent are within two standard deviations (μ ± 2σ), and about 99.7 percent lie within three standard deviations (μ ± 3σ).
An example of a Levey–Jennings chart with upper and lower limits of one and two times the standard deviation. A Levey–Jennings chart is a graph that quality control data is plotted on to give a visual indication whether a laboratory test is working well. The distance from the mean is measured in standard deviations.
In these examples, we will take the values given as the entire population of values. The data set [100, 100, 100] has a population standard deviation of 0 and a coefficient of variation of 0 / 100 = 0; The data set [90, 100, 110] has a population standard deviation of 8.16 and a coefficient of variation of 8.16 / 100 = 0.0816
The instrument detection limit (IDL) is the analyte concentration that is required to produce a signal greater than three times the standard deviation of the noise level. This may be practically measured by analyzing 8 or more standards at the estimated IDL then calculating the standard deviation from the measured concentrations of those standards.
In metrology, measurement uncertainty is the expression of the statistical dispersion of the values attributed to a quantity measured on an interval or ratio scale.. All measurements are subject to uncertainty and a measurement result is complete only when it is accompanied by a statement of the associated uncertainty, such as the standard deviation.
In statistics, the 68–95–99.7 rule, also known as the empirical rule, and sometimes abbreviated 3sr or 3 σ, is a shorthand used to remember the percentage of values that lie within an interval estimate in a normal distribution: approximately 68%, 95%, and 99.7% of the values lie within one, two, and three standard deviations of the mean ...
Standard deviation is a widely used measure of the spread or dispersion of a dataset. It quantifies the average amount of variation or deviation of individual data points from the mean of the dataset. It uses squared deviations, and has desirable properties. Standard deviation is sensitive to extreme values, making it not robust. [7]