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An opportunistic infection is a serious infection caused by pathogens (bacteria, ... opportunistic infections are a leading cause of HIV/AIDS-related deaths. [49]
Additionally, people with AIDS often have systemic symptoms of infection like fevers, sweats (particularly at night), swollen glands, chills, weakness, and weight loss. [13] [14] The specific opportunistic infections that AIDS patients develop depend in part on the prevalence of these infections in the geographic area in which the patient lives.
Most of these conditions are opportunistic infections that are easily treated in healthy people. The staging system is different for adults and adolescents and children. [2] Stage I: HIV disease is asymptomatic and not categorized as AIDS. Stage II: include minor mucocutaneous manifestations and recurrent upper respiratory tract infections.
Over time, they cause acquired immunodeficiency syndrome (AIDS), [1] [2] a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. [3] Without treatment, the average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. [4]
Despite these statistics, overall, new HIV infections and AIDS-related deaths have substantially decreased in this region since 2010. [228] Eastern Europe and central Asia has observed a 43% increase in new HIV infections and 32% increase in AIDS-related deaths since 2010, the highest of all global regions. [228]
In 1993, the CDC added pulmonary tuberculosis, recurrent pneumonia and invasive cervical cancer [2] to the list of clinical conditions in the AIDS surveillance case definition published in 1987 [3] and expanded the AIDS surveillance case definition to include all HIV-infected persons with CD4+ T-lymphocyte counts of fewer than 200 cells/μL or ...
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