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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Normally, HFE facilitates the binding of transferrin, which is iron's carrier protein in the blood. Transferrin levels are typically elevated at times of iron depletion (low ferritin stimulates the release of transferrin from the liver). When transferrin is high, HFE works to increase the intestinal release of iron into the blood.
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these. [44]
Chlorofluorocarbons (CFCs): when derived from methane and ethane these compounds have the formulae CCl m F 4−m and C 2 Cl m F 6−m, where m is nonzero. Hydro-chlorofluorocarbons (HCFCs): when derived from methane and ethane these compounds have the formula CCl m F n H 4−m−n and C 2 Cl x F y H 6−x−y, where m, n, x, and y are nonzero.
Perfluorocarbons dissolve relatively high volumes of gases. The high solubility of gases is attributed to the weak intermolecular interactions in these fluorocarbon fluids. [12] The table shows values for the mole fraction, x 1, of nitrogen dissolved, calculated from the Blood–gas partition coefficient, at 298.15 K (25 °C), 0.101325 MPa. [13]
This misconception may derive from urine bacterial screening tests, which return "negative" when bacteria levels are low, but nonzero. [ 283 ] Sudden immersion into freezing water does not typically cause death by hypothermia , but rather from the cold shock response , which can cause cardiac arrest , heart attack , or hyperventilation leading ...
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
1,2-Dichlorotetrafluoroethane, or R-114, also known as cryofluorane , is a chlorofluorocarbon (CFC) with the molecular formula ClF 2 CCF 2 Cl. Its primary use has been as a refrigerant. It is a non-flammable gas with a sweetish, chloroform-like odor with the critical point occurring at 145.6 °C and 3.26 MPa. When pressurized or cooled, it is a ...