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Acetylcysteine is the N-acetyl derivative of the amino acid L-cysteine, and is a precursor in the formation of the antioxidant glutathione in the body. The thiol (sulfhydryl) group confers antioxidant effects and is able to reduce free radicals .
In enzymology, a cysteine-S-conjugate N-acetyltransferase (EC 2.3.1.80) is an enzyme that catalyzes the chemical reaction acetyl-CoA + an S-substituted L-cysteine ⇌ {\displaystyle \rightleftharpoons } CoA + an S-substituted N-acetyl-L-cysteine
A simplified reaction mechanism for N-acetylglutamate synthase (NAGS). Two mechanisms for N-acetyltransferase function have been proposed: a two-step, ping-pong mechanism involving transfer of the relevant acetyl group to an activated cysteine residue [10] and a one-step mechanism through direct attack of the amino nitrogen on the carbonyl group. [11]
N-Acetyl-L-tyrosine is an amino acid, an N-acetyl derivative of tyrosine. It is used for parenteral nutrition and as a dietary supplement. [1] [2] [3] See also.
N-acetyltransferase (NAT) is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines, arylhydroxylamines and arylhydrazines. [ 1 ] [ 2 ] [ 3 ] They have wide specificity for aromatic amines , particularly serotonin , and can also catalyze acetyl transfer between arylamines without CoA.
Proposed revision: "Acetylcysteine, also known as N-acetylcysteine (NAC) or N-acetyl-L-cysteine, is a mucolytic compound that is used as a medication for the treatment of paracetamol (acetaminophen) overdose and to loosen excessively thick mucus in individuals with cystic fibrosis or chronic obstructive pulmonary disease. [1] "