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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). [5] Signs and symptoms may include blood in the stool , a change in bowel movements , weight loss, abdominal pain and fatigue. [ 9 ]
The American Cancer Society recommends that all adults over 45 be tested regularly for colon cancer, even if they have no symptoms. People older than 50 are still at a greater risk of developing ...
Many seborrheic keratoses on the back of a person with Leser–Trélat sign due to colon cancer. The Leser–Trélat sign is the explosive onset of multiple seborrheic keratoses [1] (many pigmented skin lesions), [2] [3] often with an inflammatory base. This can be a sign of internal malignancy as part of a paraneoplastic syndrome. In addition ...
Celine Dion, who on Thursday announced she's battling Stiff Person Syndrome, has been diagnosed with an incurable neurological disease so extremely rare that, according to the famed Cleveland ...
Stiff person syndrome, which occurs in about one in 1 million people, is characterized by progressive muscle rigidity which leads to impaired mobility, muscle spasms, postural deformities and ...
Gardner's syndrome (also known as Gardner syndrome, familial polyposis of the colon, [1] or familial colorectal polyposis [2]) is a subtype of familial adenomatous polyposis (FAP). Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. [ 3 ]
Like many autoimmune diseases, SPS exists on a spectrum and, as a result, symptoms can look quite different in different people, Dr. Scott Newsome, head of the Johns Hopkins Stiff Person Syndrome ...