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If used during pregnancy, it can cause harm to the developing fetus. [5] However, it appears to be safe for use during breastfeeding. [8] Gentamicin is a type of aminoglycoside [5] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria. [5]
Nevertheless, during pregnancy, colonization can be temporary, intermittent, or continual. [12] Because of this the GBS colonization status of women can change during pregnancy, only cultures carried out ≤5 weeks before delivery and predict quite accurately the GBS carrier status at delivery. [62]
Aminoglycosides are in pregnancy category D, [18] that is, there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Common antibiotics include a combination of ampicillin and gentamicin following vaginal delivery or clindamycin and gentamicin in those who have had a C-section. [1] In those who are not improving with appropriate treatment, other complications such as an abscess should be considered. [1] In 2015, about 11.8 million maternal infections occurred ...
Listeriosis is a bacterial infection most commonly caused by Listeria monocytogenes, [1] although L. ivanovii and L. grayi have been reported in certain cases. Listeriosis can cause severe illness, including severe sepsis, meningitis, or encephalitis, sometimes resulting in lifelong harm and even death.
Gentamicin + clindamycin However, there is not enough evidence to support the most efficient antimicrobial regimen. [ 16 ] Starting the treatment during the intrapartum period is more effective than starting it postpartum; it shortens the hospital stay for the mother and the neonate. [ 17 ]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Use during pregnancy may result in permanent deafness in the developing baby. [3] Use appears to be safe while breastfeeding. [4] It is not recommended in people with myasthenia gravis or other neuromuscular disorders. [4] Streptomycin is an aminoglycoside. [3]