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Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
Chronic Exposure: Under some circumstances methemoglobinemia occurs in individuals when the nitrate is converted by bacteria in the stomach to nitrite. Nausea, vomiting, dizziness, rapid heart beat, irregular breathing, convulsions, coma, and death can occur should this conversion take place.
The nitrate-nitrite-nitric oxide pathway elevates nitric oxide through the sequential reduction of dietary nitrate derived from plant-based foods. [13] Nitrate-rich vegetables, in particular leafy greens, such as spinach and arugula , and beetroot , have been shown to increase cardioprotective levels of nitric oxide with a corresponding ...
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Uranyl nitrate is an oxidizing and highly toxic compound. When ingested, it causes severe chronic kidney disease and acute tubular necrosis and is a lymphocyte mitogen. Target organs include the kidneys, liver, lungs and brain. It also represents a severe fire and explosion risk when heated or subjected to shock in contact with oxidizable ...
In the NO − 3 anion, the oxidation state of the central nitrogen atom is V (+5). This corresponds to the highest possible oxidation number of nitrogen. Nitrate is a potentially powerful oxidizer as evidenced by its explosive behaviour at high temperature when it is detonated in ammonium nitrate (NH 4 NO 3), or black powder, ignited by the shock wave of a primary explosive.
The nitrates are used for the treatment and prevention of angina and acute myocardial infarction, while molsidomine acts too slowly to be useful for the treatment of acute angina. [2] For quick action in the treatment of angina, glyceryl trinitrate is used in form of a sublingual spray (nitro spray) or as soft capsules to be crunched.
Industrial production of sodium nitrite follows one of two processes, the reduction of nitrate salts, or the oxidation of lower nitrogen oxides. One method uses molten sodium nitrate as the salt, and lead which is oxidized, while a more modern method uses scrap iron filings to reduce the nitrate. [4] [84] NaNO 3 + Pb → NaNO 2 + PbO