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Leukapheresis may be performed to obtain the patient's own blood cells for a later transplant. White blood cells may be removed to protect them from damage before high-dose chemotherapy, then transfused back into the patient, in the treatment of advanced breast cancer. [1] Another novel use of cells obtained through leukapheresis is to ...
Leukapheresis – leukocytes (white blood cells). Leukopheresis is the removal of PMNs , basophils, eosinophils for transfusion into patients whose PMNs are ineffective or where traditional therapy has failed.
An excess of white blood cells is usually due to infection or inflammation. Less commonly, a high white blood cell count could indicate certain blood cancers or bone marrow disorders. The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important subset of the complete blood count.
Granulocytes are most often collected through leukapheresis, a process that separates the donor's white blood cells from their red blood cells and plasma. Donors may be given corticosteroids or granulocyte colony-stimulating factor to increase their granulocyte count prior to the blood collection. Granulocytes have a short shelf life and it is ...
A blood cell (also called a hematopoietic cell, hemocyte, or hematocyte) is a cell produced through hematopoiesis and found mainly in the blood. Major types of blood cells include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).
With a diameter of 15–22 μm, monocytes are the largest cell type in peripheral blood. [2] [3] Monocytes are mononuclear cells and the ellipsoidal nucleus is often lobulated/indented, causing a bean-shaped or kidney-shaped appearance. [4] Monocytes compose 2% to 10% of all leukocytes in the human body.
Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.. In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and towards the ...
Leukocyte apheresis is a medical device therapy (selective granulocyte/monocyte adsorptive {GMA} apheresis; GMDN [1] code: 47306) for the treatment of inflammation of the colon. It works by removing from the blood a group of white blood cells called activated leukocytes [ 2 ] that play a key role in the inflammatory stages of ulcerative colitis ...