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Spina bifida (SB; / ˈ s p aɪ n ə ˈ b ɪ f ɪ d ə /; [9] Latin for 'split spine') [10] is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. [1] There are three main types: spina bifida occulta, meningocele and myelomeningocele. [1]
Historically, spina bifida was not detected before birth. Maternal serum screening of elevated alpha-fetoprotein at 16 to 18 weeks of gestation, followed by amniocentesis allowed detection of a minority of cases. A better option is the assessment of Acetyl choline Esterase form amniotic fluid. Today, detection rate is 98% at the time of an ...
It is most often discovered during the routine scan typically performed when a fetus is around 18 weeks old, according to the clinic. Spina bifida can affect a child’s lower leg strength and ...
Spina bifida occulta means hidden split spine. [20] In this type of neural tube defect, the meninges do not herniate through the opening in the spinal canal. [19] The most frequently seen form of spina bifida occulta is when parts of the bones of the spine, called the spinous process, and the neural arch appear abnormal on a radiogram, without ...
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The photograph was taken during a medical procedure to fix the spina bifida lesion of a 21-week-old fetus. The operation was performed by a surgical team at Vanderbilt University in Nashville. The team, Dr. Joseph Bruner and Dr. Noel Tulipan, had been developing a technique for correcting certain fetal problems in mid-pregnancy.
Risks of fetal surgery, specifically prenatal spina bifida repair, include premature rupture of membranes, uterine rupture in future pregnancies, premature birth and intraspinal inclusion cysts or a tethered cord in the fetus or newborn baby. [4] Open fetal surgery has proven to be reasonably safe for the mother. [3]
Hysterotomy is a technique used during fetal surgery to access the fetus in the pregnant uterus in order to treat a birth defect such as spina bifida. [13] A standard hysterotomy remains the gold-standard for the closure of a fetal spina bifida because it is the safest and most effective when compared to mini-hysterectomies and a percutaneous ...