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  2. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.

  3. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  4. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    Post-acute withdrawal syndrome (PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [1] [2] opiates, benzodiazepines, barbiturates, and other substances.

  5. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Opioid addiction includes insufflation or injection, rather than taking opioids orally as prescribed for medical reasons. [ 94 ] In European nations such as Austria, Bulgaria, and Slovakia, slow-release oral morphine formulations are used in opiate substitution therapy (OST) for patients who do not well tolerate the side effects of ...

  6. Not Enough Doctors Are Treating Heroin Addiction With A Life ...

    projects.huffingtonpost.com/dying-to-be-free...

    One way to explain the stubbornness of the epidemic is to look at the availability of the maintenance medication buprenorphine, sold most commonly under the brand name Suboxone. Taking the medication (or methadone), along with counseling, is an opioid addict’s best chance for recovery, public health experts say.

  7. Noah Cyrus, 22, reveals Xanax addiction: 'It just kind of ...

    www.aol.com/lifestyle/noah-cyrus-22-reveals...

    Noah Cyrus is opening up about life in recovery as she reveals an addiction to Xanax for the first time.. The 22-year-old singer has long been in the public eye as a result of her famous family ...

  8. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    In humans, N-demethylation of oxycodone to noroxycodone by CYP3A4 is the major metabolic pathway, accounting for 45% ± 21% of a dose of oxycodone, while O-demethylation of oxycodone into oxymorphone by CYP2D6 and 6-ketoreduction of oxycodone into 6-oxycodols represent relatively minor metabolic pathways, accounting for 11% ± 6% and 8% ± 6% ...

  9. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.