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This makes the hydroxymethyl group an alcohol. It has the identical chemical formula with the methoxy group (−O−CH 3) that differs only in the attachment site and orientation to the rest of the molecule. However, their chemical properties are different. [1] [2] Hydroxymethyl is the side chain of encoded amino acid serine. [3]
A common method for hydroxymethylation involves the reaction of formaldehyde with active C-H and N-H bonds: R 3 C-H + CH 2 O → R 3 C-CH 2 OH R 2 N-H + CH 2 O → R 2 N-CH 2 OH. A typical active C-H bond is provided by a terminal acetylene [1] or the alpha protons of an aldehyde. [2]
The chain starts with a hydroxymethyl group −CH 2 −OH and ends with an hydrogen, in place of the respective methylene bridges. The other two carbon atoms of each pyrrole cycle are connected to an acetic acid group −CH 2 −COOH and a propionic acid group −CH 2 −CH 2 −COOH, in that order. [1]
Cyclohexylmethanol is an organic compound with the formula C 6 H 11 −CH 2 −OH. It is a cyclohexane ring functionalized with an alcohol , specifically a hydroxymethyl group. The compound is a colorless liquid, although commercial samples can appear yellow.
The useful buffer range for tris (pH 7–9) coincides with the physiological pH typical of most living organisms. This, and its low cost, make tris one of the most common buffers in the biology/biochemistry laboratory. Tris is also used as a primary standard to standardize acid solutions for chemical analysis.
9-Anthracenemethanol is the derivative of anthracene with a hydroxymethyl group (CH 2 OH) attached to the 9-position. It is a colorless solid that is soluble in ordinary organic solvents. The compound can be prepared by hydrogenation of 9-anthracenecarboxaldehyde. It is a versatile precursor to supramolecular assemblies.
Furfuryl alcohol is an organic compound containing a furan substituted with a hydroxymethyl group. It is a colorless liquid, but aged samples appear amber. It possesses a faint odor of burning and a bitter taste. It is miscible with but unstable in water. It is soluble in common organic solvents. [4]
Salicyl alcohol (saligenin) is an organic compound with the formula C 6 HOH(CH 2 OH. It is a white solid that is used as a precursor in organic synthesis . [ 3 ]
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