Ad
related to: how is scleroderma inherited from spouse diagnosed pictures- Urgency to Treat
The Importance of
Risk Assessment
- Commitment to Patients
Learn About Support
for Your Patients
- Health Resource Tools
Visit Site for PAH
Digital Health Tools
- Foundational Pathways
Learn About Foundational
Pathways of PAH
- Urgency to Treat
Search results
Results From The WOW.Com Content Network
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed with the condition. Each disorder is also categorized by its acceptance as an autoimmune condition into four levels: confirmed, probable, possible, and uncertain.
In 1982, while working as a management consultant for McKinsey & Co. Inc., Monsky was diagnosed with scleroderma and was told she had only two years to live. The rare disease hardens the skin and internal organs of young women of child-bearing age causing disfigurement, and is potentially fatal.
Scleromyositis, is an autoimmune disease (a disease in which the immune system attacks the body). People with scleromyositis have symptoms of both systemic scleroderma and either polymyositis or dermatomyositis, and is therefore considered an overlap syndrome.
Linear scleroderma generally first appears in young children. [3] Frontal linear scleroderma (also known as en coup de sabre or morphea en coup de sabre) is a type of linear scleroderma characterized by a linear band of atrophy and a furrow in the skin that occurs in the frontal or frontoparietal scalp.
Scleroderma, a hardening and tightening of the skin on trunk and extremities of the body, is prevalent. People diagnosed with this disorder usually have small, fragile bodies, like those of older adults. The head is usually large relative to the body, with a narrow, wrinkled face and a beak nose.
Scleroderma results from the overproduction of collagen in affected tissues, one study claims that there is an increased density of Topoisomerase I sites in the collagen genes, and that the antibodies may be altering transcription at these loci. [7] ATA correlates with rapid progression of disease. [8]
Ad
related to: how is scleroderma inherited from spouse diagnosed pictures