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Uncommon side effects include fatigue and malaise, behavioral changes, paresthesias and seizures, muscle cramps, and nose bleeds. Rare (may affect up to 1 in 10,000 people taking montelukast) but serious side effects include behavioral changes (including suicidal thoughts), angioedema, erythema multiforme, and liver problems. [3] [14]
However, research does not show whether the binding leads to the harmful side effects from the drug. A sample of the drug Singulair made by Merck & Co. is seen in New York March 9, 2009
The adverse effects of zafirlukast are very similar to montelukast. There is a database for safety which incorporates more than 4000 volunteers and 1723 patients which were asthmatic. Some of the side effects are similar to that of montelukast for example headache, infection, abdominal pain, fever, and multiple others. [10]
Singulair was a blockbuster product for Merck after its launch in 1998, offering relief ... Marschallinger said the new data bolsters reports from people who reported suffering side effects ...
Zafirlukast is FDA-approved for the prevention and treatment of asthma in adults and children older than 5 years old. [1] Like other leukotriene receptor antagonists, zafirlukast is thought to be useful for the long-term treatment of asthma, but it is generally less effective than inhaled glucocorticoids as monotherapy (which are the standard of care) or long-acting beta-2 agonists in ...
When combined with inhaled steroids, β adrenoceptor agonists can improve symptoms. [1] [2] In children this benefit is uncertain and they may be potentially harmful. [2]They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. [3]