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Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
Airway clearance therapy is treatment that uses a number of airway clearance techniques to clear the respiratory airways of mucus and other secretions. [1] Several respiratory diseases cause the normal mucociliary clearance mechanism to become impaired resulting in a build-up of mucus which obstructs breathing, and also affects the cough reflex .
Mucokinetics: increase mucociliary transport (clearance) and transportability of mucus by cough [2] Mucoregulators : suppress underlying mechanisms of mucus hypersecretion [ 2 ] Alternatively, attacking the affinity between secretions and the biological surfaces is another avenue, which is used by abhesives and surfactants .
Ambroxol is indicated as "secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breathe freely and deeply". [2] Ambroxol hydrochloride tablets in Japan
Pulmonary hygiene, also referred to as pulmonary toilet, [1] is a set of methods used to clear mucus and secretions from the airways.The word pulmonary refers to the lungs.The word toilet, related to the French toilette, refers to body care and hygiene; this root is used in words such as toiletry that also relate to cleansing.
The development of heated humidified high flow started in 1999 with Vapotherm introducing the concept of high flow use with race horses. [2]High flow was approved by the U.S. Food and Drug Administration in the early 2000s and used as an alternative to positive airway pressure for treatment of apnea of prematurity in neonates. [3]