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Your healthcare provider may give you additional instructions depending on what you’re taking metformin for — i.e., as a diabetes medication or a weight loss treatment. ... The most common ...
Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. ... 24/7 Help. For premium support please call:
Metformin does not cause kidney damage by itself, however there is a risk of serious side effects if metformin is used when you have impaired renal function, Dr. Gupta notes.
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [ 76 ] [ 81 ] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Although it must be used with caution in patients with impaired liver or kidney function, Metformin, a biguanide, has become the most commonly used agent for type 2 diabetes in children and teenagers. Among common diabetic drugs, Metformin is the only widely used oral drug that does not cause weight gain. [9]
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...