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The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP). JUPITER was the first clinical trial to indicate that statin therapy may provide benefit to patients with low-to-normal LDL levels and no known cardiovascular disease.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
For the figure that shows high sensitivity and low specificity, there are 3 FN and 8 FP. Using the fact that positive results = true positives (TP) + FP, we get TP = positive results - FP, or TP = 40 - 8 = 32. The number of sick people in the data set is equal to TP + FN, or 32 + 3 = 35. The sensitivity is therefore 32 / 35 = 91.4%.
MODY 3 or HNF1A-MODY is a form of maturity-onset diabetes of the young.It is caused by mutations of the HNF1-alpha gene, a homeobox gene on human chromosome 12.This is the most common type of MODY in populations with European ancestry, [1] accounting for about 70% of all cases in Europe.
There is a direct relationship between high levels of drinking alcohol and cardiovascular disease. [3] Drinking at low levels without episodes of heavy drinking may be associated with a reduced risk of cardiovascular disease, [ 50 ] but there is evidence that associations between moderate alcohol consumption and protection from stroke are non ...
Apart from these classical risk factors, several unconventional risk factors have also been studied including high serum fibrinogen, high c-reactive protein (CRP), chronic inflammatory conditions, hypovitaminosis D, high lipoprotein A levels, serum homocysteine etc. [38] [39] Smoking and obesity are associated with about 36% and 20% of cases ...
CRP C-Reactive Protein: Level of inflammation with the body. If the immune system is fighting an infection or illness, CRP will be higher. CBC (UK: FBC) Complete Blood Count (UK: Full Blood Count) Analysis of 15 different blood test readings to provide information about overall health. TSH Thyroid-stimulating hormone
Chronic spontaneous urticaria (CSU) also known as Chronic idiopathic urticaria (CIU) is defined by the presence of wheals, angioedema, or both for more than six weeks.The most common symptoms of chronic spontaneous urticaria are angioedema and hives that are accompanied by itchiness.