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A biomaterial is a substance that has been engineered to interact with biological systems for a medical purpose – either a therapeutic (treat, augment, repair, or replace a tissue function of the body) or a diagnostic one.
Other trends include engineering bioceramics for specific tasks. Ongoing research involves the chemistry, composition, and micro- and nanostructures of the materials to improve their biocompatibility. [16] [17] [18]
By definition, biodegradable materials are formed or organic compounds which can thus be broken down by living organisms, such as bacteria, fungi, or water molds, and reabsorbed by the natural environment. [13] Whether a material is biodegradable is determined by its chemical structure, not the origin of the material from which it is made. [14]
At first, the study of biometals was referred to as bioinorganic chemistry. Each branch of bioinorganic chemistry studied separate, particular sub-fields of the subject. However, this led to an isolated view of each particular aspect in a biological system. This view was revised into a holistic approach of biometals in metallomics. [2]
Hardness is one of the most important parameters for comparing properties of materials. It is used for finding the suitability of the clinical use of biomaterials. Biomaterial hardness is desirable as equal to bone hardness. If higher than the biomaterial, then it penetrates in the bone. Higher hardness results in less abrasion.
Biomimetic materials in tissue engineering are materials that have been designed such that they elicit specified cellular responses mediated by interactions with scaffold-tethered peptides from extracellular matrix (ECM) proteins; essentially, the incorporation of cell-binding peptides into biomaterials via chemical or physical modification. [3]
In the literature, one quite often stumbles upon the adjective form, ‘biocompatible’. However, according to Williams’ definition, this does not make any sense because biocompatibility is contextual, i.e. much more than just the material itself will determine the clinical outcome of the medical device of which the biomaterial is a part.
The ASTM D6866 method has been developed to certify the biologically derived content of bioplastics. Cosmic rays colliding with the atmosphere mean that some of the carbon is the radioactive isotope carbon-14. CO 2 from the atmosphere is used by plants in photosynthesis, so new plant material will contain both carbon-14 and carbon-12.