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Lorcaserin, marketed under the brand name Belviq, [4] [5] was a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus , a region of the brain which is known to control appetite. [ 6 ]
Lorcaserin (Belviq) was FDA approved for weight loss but was withdrawn from the market because a safety clinical trial shows an increased occurrence of cancer. [ 11 ] Cannabinoid receptor antagonists were developed to treat obesity because researchers noticed that cannabinoid agonists (such as THC , the main pharmacologically active component ...
Arena Pharmaceuticals (ARNA) announced, as expected, the U.S. Food and Drug Administration did not approve its weight loss drug Lorcaserin for patients who are obese and overweight because the ...
[2] [3] Benzarone: 1992 Germany Hepatitis. [3] Benziodarone: 1964 France, UK Jaundice. [3] Beta-ethoxy-lacetanilanide: 1986 Germany Renal toxicity, animal carcinogenicity. [3] Bezitramide: 2004 Netherlands Risk of fatal overdose [10] Bithionol: 1967 US Dermatologic toxicity. [3] Brotizolam: 1989 UK Animal carcinogenicity. [3] Bromfenac: 1998 US
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The FDA has banned red dye No. 3, as the synthetic additive is known to cause cancer. Nutritionists Ilana Muhlstein and Robin DeCicco discuss what this means for American health.
A higher number of cardiovascular events has been observed in people taking sibutramine versus control (11.4% vs. 10.0%). [16] In 2010, the FDA noted the concerns that sibutramine increases the risk of heart attacks and strokes in patients with a history of cardiovascular disease.
Former day care worker Melissa Calusinski has served 16 years of a 31-year prison sentence for a crime she insists she didn't commit — a murder that may not have even happened.