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An inflammatory cytokine is a type of cytokine (a signaling molecule) that is secreted from immune cells and certain other cell types that promotes inflammation. Inflammatory cytokines are predominantly produced by T helper cells ( T h ) and macrophages and involved in the upregulation of inflammatory reactions. [ 1 ]
MIP-1α and MIP-1β are major factors produced by macrophages and monocytes after they are stimulated with bacterial endotoxin [5] or proinflammatory cytokines such as IL-1β. [4] But it appears that they can be expressed by all hematopoietic cells and some tissue cells such as fibroblasts, epithelial cells, vascular smooth muscle cells or ...
Cytokine-induced killer cells (CIK) cells are a group of immune effector cells featuring a mixed T- and natural killer (NK) cell-like phenotype.They are generated by ex vivo incubation of human peripheral blood mononuclear cells (PBMC) or cord blood mononuclear cells with interferon-gamma (), anti-CD3 antibody, recombinant human interleukin (IL)-1 and recombinant human interleukin (IL)-2.
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. [1] Professor Marshall Urist and Professor Hari Reddi discovered their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body.
Interleukin 3 (IL3) is a cytokine that regulates hematopoiesis by controlling the production, differentiation and function of granulocytes and macrophages. [ 15 ] [ 16 ] The protein, which exists in vivo as a monomer, is produced in activated T cells and mast cells, [ 15 ] [ 16 ] and is activated by the cleavage of an N-terminal signal sequence.
53603 Ensembl ENSG00000145777 ENSMUSG00000024379 UniProt Q969D9 Q9JIE6 RefSeq (mRNA) NM_033035 NM_138551 NM_021367 RefSeq (protein) NP_149024 NP_612561 NP_067342 Location (UCSC) Chr 5: 111.07 – 111.08 Mb Chr 18: 32.95 – 32.95 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-2 -like cytokine, alarmin, and growth factor ...