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The cut surface of a 3.9 × 3.5 × 2.5 cm tumor is triangular, with a bulging peripheral portion and a somewhat fibrotic center. It was surrounded by the heart, left lower lobe of the lung, aorta, esophagus, and diaphragm, and had been 1.8 cm in diameter 7 years before. Micrograph of a carotid body tumor with the characteristic Zellballen. H&E ...
Tumors of the paraganglionic tissues are known as paragangliomas, though this term tends to imply the nonchromaffin type, and can occur at a number of sites throughout the body. Chromaffin paragangliomas are issued from chromaffin cells, and are known as pheochromocytomas .
The carotid body is situated on the posterior aspect of the bifurcation of the common carotid artery. [3] The carotid body is made up of two types of cells, called glomus cells: glomus type I cells are peripheral chemoreceptors, and glomus type II cells are sustentacular supportive cells. Glomus type I cells are derived from the neural crest. [4]
[1] [13] Stereotactic body radiotherapy (SBRT) is a promising treatment option for benign spinal nerve sheath tumors, though more research is currently needed to determine effectiveness across different tumor types and to establish adequate clinical guidelines.
An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [1] [2]The material consists of mostly macrophage cells, [3] [4] or debris, containing lipids, calcium and a variable amount of fibrous connective tissue.
The carotid body is not labelled but is located within the wall of the internal carotid artery near the bifurcation of the common carotid artery. Glomus type I cells are the chemoreceptor cells found in the carotid body. Glomus cells are the cell type mainly located in the carotid bodies and aortic bodies. Glomus type I cells are peripheral ...
Carotid bodies are considered the primary peripheral chemoreceptor and have been shown to contribute more to a hypoxic response. However, in the chronic absence of the carotid body, the aortic body is able to perform a similar respiratory regulatory role, suggesting that it possesses efficacious mechanisms of signal transduction as well. [5]
Some of these conditions include xanthomas: lesions that are seen in hyperlipidemia; xanthogranuloma: benign skin lesions; fat necrosis: areas of trauma where adipose tissue has been disrupted; dermatofibrosa: benign skin tumor characterized by fibrous components; granulomatous diseases such as sarcoidosis.