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  2. Adenosine - Wikipedia

    en.wikipedia.org/wiki/Adenosine

    Adverse effects associated with adenosine administration are primarily due to its activation of adenosine receptors on vascular tissue, resulting in vasodilation. Side effects of adenosine include skin flushing, lightheadedness, nausea, sweating, nervousness, numbness, and a sense of impending doom. These effects are typically very short-lived ...

  3. Adenosine monophosphate - Wikipedia

    en.wikipedia.org/wiki/Adenosine_monophosphate

    Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide. AMP consists of a phosphate group, the sugar ribose , and the nucleobase adenine . It is an ester of phosphoric acid and the nucleoside adenosine . [ 1 ]

  4. Anti-asthmatic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-asthmatic_agent

    Common side effects of inhaled β2-adrenergic agonists include ... inhibiting phosphodiesterase degradation action of cyclic 3′,5′-adenosine monophosphate (cAMP ...

  5. PDE4 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE4_inhibitor

    A phosphodiesterase-4 inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate (cAMP). It is a member of the larger family of PDE inhibitors. The PDE4 family of enzymes are the most prevalent PDE in immune cells. They are predominantly ...

  6. Cyclic adenosine monophosphate - Wikipedia

    en.wikipedia.org/wiki/Cyclic_adenosine_monophosphate

    cAMP represented in three ways Adenosine triphosphate. Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger, or cellular signal occurring within cells, that is important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms ...

  7. AMP-activated protein kinase - Wikipedia

    en.wikipedia.org/wiki/AMP-activated_protein_kinase

    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis, largely to activate glucose and fatty acid uptake and oxidation when cellular energy is low.

  8. PDE3 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE3_inhibitor

    PDE3 inhibitors are a type of phosphodiesterase inhibitors.Inhibition of the PDE isoenzyme 3 leads to an increase of intracellular concentrations of the second messenger cyclic adenosine monophosphate (cAMP). cAMP mediates the phosphorylation of protein kinases, which in turn activates cardiac calcium channels.

  9. Antimanic drugs - Wikipedia

    en.wikipedia.org/wiki/Antimanic_drugs

    Lithium is suggested to affect multiple neurotransmitter systems including noradrenaline, dopamine, serotonin, and gamma aminobutyric acid, along with second messenger systems including cyclic adenosine monophosphate and cyclic guanosine monophosphate.