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  2. Timeline of peptic ulcer disease and Helicobacter pylori

    en.wikipedia.org/wiki/Timeline_of_peptic_ulcer...

    First report of resistance of H. pylori to the antibiotic metronidazole. [52] Resistance of H. pylori to treatment will lead to the development of many different antibiotic and proton pump inhibitor regimens for eradication. [53] 1992 Fukuda et al. prove ingestion of H. pylori causes gastritis in rhesus monkeys. [4]

  3. Helicobacter pylori - Wikipedia

    en.wikipedia.org/wiki/Helicobacter_pylori

    Helicobacter pylori, previously known as Campylobacter pylori, is a gram-negative, flagellated, helical bacterium. Mutants can have a rod or curved rod shape that exhibits less virulence . [ 1 ] [ 2 ] Its helical body (from which the genus name Helicobacter derives) is thought to have evolved to penetrate the mucous lining of the stomach ...

  4. Barry Marshall - Wikipedia

    en.wikipedia.org/wiki/Barry_Marshall

    Marshall did not develop antibodies to H. pylori, suggesting that innate immunity can sometimes eradicate acute H. pylori infection. Marshall's illness and recovery, based on a culture of organisms extracted from a patient, fulfilled Koch's postulates for H. pylori and gastritis, but not for peptic ulcers.

  5. Anti-ulcer agents - Wikipedia

    en.wikipedia.org/wiki/Anti-ulcer_agents

    Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion. The anti-ulcer dosing regimens generally repair ...

  6. Helicobacter - Wikipedia

    en.wikipedia.org/wiki/Helicobacter

    Helicobacter heilmannii sensu lato (i.e. H. heilmanni s.l.) is a grouping of non-H. pylori Helicobacter species that take as part of their definition a similarity to H. pylori in being associated with the development of stomach inflammation, stomach ulcers, [11] duodenum ulcers, [12] stomach cancers that are not lymphomas, and extranodal ...

  7. Martin J. Blaser - Wikipedia

    en.wikipedia.org/wiki/Martin_J._Blaser

    Blaser is best known [21] for his studies of Helicobacter pylori and its relationship with human diseases. [22] [23] Initially dismissive and skeptical of Nobel laureate Barry Marshall's findings of H. pylori's relationship to gastric and peptic ulcers, which Blaser described as "the most preposterous thing I’d ever heard; I thought, this guy is a madman,” [24] [25] Blaser's work ...