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  2. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    The cardioprotective effects of SGLT2 inhibitors have been attributed to the elevated ketone levels. [ 59 ] Gliflozins have been posited to exhibit protective effects on the heart, liver, kidneys, anti‐hyperlipidemic, anti‐ atherosclerotic , anti‐ obesity , anti‐ neoplastic effects in in vitro , pre‐clinical, and clinical studies.

  3. Soluble guanylate cyclase stimulator - Wikipedia

    en.wikipedia.org/wiki/Soluble_guanylate_cyclase...

    Soluble guanylate cyclase (sGC) stimulators are a class of drugs developed to treat heart failure, pulmonary hypertension, and other diseases. The first-in-class medication was riociguat, approved in 2013 for pulmonary hypertension. [1] [2] They have also been investigated for hypertension, systemic sclerosis, and sickle cell disease. [3] [1]

  4. Ertugliflozin - Wikipedia

    en.wikipedia.org/wiki/Ertugliflozin

    Ertugliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor [3] [4] and is in the class of drugs known as gliflozins. [5] In the United States, it was approved by the Food and Drug Administration for use as a monotherapy and as a fixed dose combination with either sitagliptin or with metformin. [6]

  5. Sotagliflozin - Wikipedia

    en.wikipedia.org/wiki/Sotagliflozin

    Other common side effects include diabetic ketoacidosis, diarrhea, and genital infection in men. [ 2 ] Sotagliflozin was approved for medical use in the European Union in April 2019, as Zynquista , for the treatment for type 1 diabetes , [ 2 ] and in the United States in May 2023, [ 3 ] to reduce the risk of death due to heart failure.

  6. Luseogliflozin - Wikipedia

    en.wikipedia.org/wiki/Luseogliflozin

    Luseogliflozin (trade name Lusefi) is a pharmaceutical drug (an SGLT2 inhibitor) used for the treatment of type 2 diabetes mellitus. [1] [2] It was approved for use in Japan in 2014. [1]

  7. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment