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Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death.
Cohorts for Heart and Aging Research in Genomic Epidemiology, abbreviated CHARGE, is a consortium formed to facilitate meta-analyses of genome-wide association studies of aging and cardiovascular traits, and the replication of genotype–phenotype associations identified in such studies.
The main mechanisms identified as potential biomarkers of aging are DNA methylation, loss of histones, and histone modification. The uses for biomarkers of aging are ubiquitous and identifying a physical parameter of biological aging would allow humans to determine our true age, mortality, and morbidity. [10]
The authors begin by seeking to characterize how professionals view the hallmarks of aging, including genomic instability caused by DNA damage; alterations to the epigenome that controls which genes are turned on and off; loss of healthy protein maintenance, known as proteostasis; exhaustion of stem cells; and the production of inflammatory ...
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease is a peer-reviewed open access scientific journal and an official journal of the American Heart Association. [1] Since 2015, it is also published with John Wiley & Sons .
Ageing Research Reviews is a peer-reviewed scientific journal publishing review articles covering research on ageing, aging-associated diseases, and human life expectancy. The editor-in-chief is Claudio Franceschi ( University of Bologna ).
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The Journal of Cardiovascular Nursing is a bimonthly peer-reviewed nursing journal covering cardiac nursing. It is published by Lippincott Williams & Wilkins and was established in 1986, with Barbara Riegel as its founding editor-in-chief.