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Hypoalbuminemia (or hypoalbuminaemia) is a medical sign in which the level of albumin in the blood is low. [1] This can be due to decreased production in the liver , increased loss in the gastrointestinal tract or kidneys , increased use in the body, or abnormal distribution between body compartments.
11657 Ensembl ENSG00000163631 ENSMUSG00000029368 UniProt P02768 P07724 RefSeq (mRNA) NM_000477 NM_009654 RefSeq (protein) NP_000468 NP_033784 Location (UCSC) Chr 4: 73.4 – 73.42 Mb Chr 5: 90.61 – 90.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human serum albumin is the serum albumin found in human blood. It is the most abundant protein in human blood plasma ; it ...
22139 Ensembl ENSG00000118271 ENSMUSG00000061808 UniProt P02766 P07309 RefSeq (mRNA) NM_000371 NM_013697 RefSeq (protein) NP_000362 NP_038725 Location (UCSC) Chr 18: 31.56 – 31.6 Mb Chr 18: 20.8 – 20.81 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone ...
Albumin is a globular, water-soluble, un-glycosylated serum protein of approximate molecular weight of 65,000 daltons.Albumin (when ionized in water at pH 7.4, as found in the body) is negatively charged.
Albumin is a family of globular proteins, the most common of which are the serum albumins.All of the proteins of the albumin family are water-soluble, moderately soluble in concentrated salt solutions, and experience heat denaturation.
The consequence of low albumin can be edema since the intravascular oncotic pressure becomes lower than the extravascular space. An alternative to albumin measurement is prealbumin, which is better at detecting acute changes (half-life of albumin and prealbumin is about 2 weeks and about 2 days, respectively). [14] [15]
The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma, a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy between a low albumin and a relatively high total protein.
Hypoproteinemia is a condition where there is an abnormally low level of protein in the blood. There are several causes that all result in edema once serum protein levels fall below a certain threshold.