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The spike protein is responsible for viral entry into the host cell, a required early step in viral replication. It is essential for replication. [ 2 ] It performs this function in two steps, first binding to a receptor on the surface of the host cell through interactions with the S1 region, and then fusing the viral and cellular membranes ...
Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a protein for degradation via a proteasome. This covalent bond of ubiquitin or ubiquitin-like proteins to targeted proteins is a major mechanism for regulating protein function in eukaryotic ...
The G1/S transition is highly regulated by transcription factor p53 in order to halt the cell cycle when DNA is damaged. [5] It is a "point of no return" beyond which the cell is committed to dividing; in yeast this is called the Start point, and in multicellular eukaryotes it is termed the restriction point (R-Point).
Formation of a tert-butyl carbocation by separation of a leaving group (a bromide anion) from the carbon atom: this step is slow. [5] Recombination of carbocation with nucleophile. Nucleophilic attack: the carbocation reacts with the nucleophile. If the nucleophile is a neutral molecule (i.e. a solvent) a third step is required to complete the ...
As the finished episodes became longer, the production team were reluctant to cut the stories in order to allow for the long title sequence, so shorter versions of it were developed. [11] The episode also introduced the characters Martin Prince and his parents, Richard , Bart's teacher Edna Krabappel and Dr. J Loren Pryor.
length "The metre, symbol m, is the SI unit of length. It is defined by taking the fixed numerical value of the speed of light in vacuum c to be 299 792 458 when expressed in the unit m s −1, where the second is defined in terms of ∆ν Cs." [1]
Hasse diagram of the search graph of the algorithm for 3 variables. Given e.g. the subset = {, ¯, ¯, ¯ ¯, ¯ ¯} of the bottom-level nodes (light green), the algorithm computes a minimal set of nodes (here: {¯,}, dark green) that covers exactly .
Star Trek creator Gene Roddenberry (pictured in 1976) was hired by Paramount to create a new television series set in the same universe. As production was underway on the film Star Trek IV: The Voyage Home, Paramount executives began to work on ideas to bring Star Trek back to television, [1] hiring writer/producer Greg Strangis to develop some proposals. [2]