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The effectiveness of lubiprostone has not been established in patients who are taking a diphenylheptane opioid (e.g., methadone). [3] [12] Irritable bowel syndrome with constipation (IBS-C; a condition that causes stomach pain or cramps, bloating, and infrequent or difficult passage of stools) in women who are at least 18 years of age.
Uterotonic properties, [5] nausea vomiting, and diarrhea, [12] contraindicated for pregnancy and breast feeding [12] Buckthorn bark and berry alder buckthorn Rhamnus frangula "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents" [3] Cascara sagrada bark bearberry Rhamnus ...
The medication can also protect against stomach ulcers in people who take NSAIDs such as ibuprofen on a daily basis. [21] Misoprostol can cause nausea, nausea, stomach pain, and stomach cramps. [22] In rare cases, it may lead to uterine rupture, which requires immediate emergency surgery. [17]
Occasionally, nausea and perianal burning occur as side effects. [130] Iberogast , a multi-herbal extract, was found to be superior in efficacy to placebo. [ 162 ] A comprehensive meta-analysis using twelve random trials resulted that the use of peppermint oil is an effective therapy for adults with irritable bowel syndrome.
Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are gastroenteritis and other gastrointestinal disorders , food poisoning , motion sickness , dizziness , migraine , fainting , low blood sugar , anxiety , hyperthermia , dehydration and lack of sleep .
The neurotransmitters implicated in the control of nausea and vomiting include acetylcholine, dopamine, histamine (H1 receptor), substance P (NK-1 receptor), and serotonin (5-HT3 receptor). There are also opioid receptors present, which may be involved in the mechanism by which opiates cause nausea and vomiting.
Secondary causes include side effects of medications such as opiates, endocrine and metabolic disorders such as hypothyroidism, and obstruction such as from colorectal cancer [20] or ovarian cancer. [23] Celiac disease and non-celiac gluten sensitivity may also present with constipation. [5] [24] [6] Cystocele can develop as a result of chronic ...
Prucalopride is contraindicated where there is hypersensitivity to the active substance or to any of the excipients, renal impairment requiring dialysis, intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract, such as Crohn's disease, and ulcerative colitis and toxic megacolon ...