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The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
Drugs come with a recommended dose in milligrams or micrograms per kilogram of body weight, and that is used in conjunction with the patient's age and body weight to determine a safe dose. In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose.
Absorption is the journey of a drug travelling from the site of administration to the site of action. [1] [2]The drug travels by some route of administration (oral, topical-dermal, etc.) in a chosen dosage form (e.g., tablets, capsules, or in solution). [3]
A drug's characteristics make a clear distinction between tissues with high and low blood flow. Enzymatic saturation: When the dose of a drug whose elimination depends on biotransformation is increased above a certain threshold the enzymes responsible for its metabolism become saturated. The drug's plasma concentration will then increase ...
Grand Bank Nepal 2016 Acquired by Prabhu Bank [6] Janata Bank: 2019 Merged with Global IME Bank [7] KIST Bank 2014 Merged with Prabhu Bikas Bank [8] Lumbini Bank 2016 Merged with Bank of Kathmandu [9] Mega Bank Nepal: 2023 Merged with Nepal Investment Bank and renamed as Nepal Investment Mega Bank [10] Nepal Bangladesh Bank: 2022 Acquired by ...
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [1] [2] The term "effective dose" is used when measurements are taken in vivo, while "effective concentration" is used when the measurements are taken in vitro. [3] It has been stated that any ...
In pharmacokinetics, the drug accumulation ratio (R ac) is the ratio of accumulation of a drug under steady state conditions (i.e., after repeated administration) as compared to a single dose. The higher the value, the more the drug accumulates in the body. An R ac of 1 means no accumulation.