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The volume of body fluid, blood glucose, oxygen, and carbon dioxide levels are also tightly homeostatically maintained. The volume of extracellular fluid in a young adult male of 70 kg (154 lbs) is 20% of body weight – about fourteen liters. Eleven liters are interstitial fluid and the remaining three liters are plasma. [7]
The transcellular fluid is the portion of total body fluid that is formed by the secretory activity of epithelial cells and is contained within specialized epithelial-lined compartments. Fluid does not normally collect in larger amounts in these spaces, [6] [7] and any significant fluid collection in these spaces is physiologically ...
Conversely, excessive fluid intake dilutes the extracellular fluid causing the hypothalamus to register hypotonic hyponatremia conditions. When the hypothalamus detects a hypertonic extracellular environment, it causes the secretion of an antidiuretic hormone (ADH) called vasopressin which acts on the effector organ, which in this case is the ...
The extracellular fluid compartment is further subdivided into the interstitial fluid and the intravascular fluid compartments. Body fluids, bodily fluids, or biofluids, sometimes body liquids, are liquids within the body of an organism. [1] In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is ...
In a 72 kg (159 lb) body containing 40 litres of fluid, about 25 litres is intracellular, [9] which amounts to 62.5%. Jackson's texts states 70% of body fluid is intracellular. [10] Extracellular fluid (1/3 of body water) is fluid contained in areas outside of cells. For a 40-litre body, about 15 litres is extracellular, [9] which amounts to 37.5%.
The osmoreceptors have a defined functionality as neurons that are endowed with the ability to detect extracellular fluid osmolarity. Osmoreceptors have aquaporin 4 proteins spanning through their plasma membranes in which water can diffuse, from an area of high to low water concentration. If plasma osmolarity rises above 290 mOsmol/L, then ...
V ECF a = Extracellular fluid volume after fluid loss; n ECF a = Amount of substance in ECF after fluid loss; V ECF b = Extracellular fluid volume before fluid loss (approximately 20% of body weight, or by using inulin) Osm b = Body osmolarity before loss (almost equal to plasma osmolality of 275-299 milli-osmoles per kilogram [4])
The majority of fluid output occurs via the urine, approximately 1500 ml/day (approx 1.59 qt/day) in the normal adult resting state. [12] [13] Some fluid is lost through perspiration (part of the body's temperature control mechanism) and as water vapor in exhaled air. These are termed "insensible fluid losses" as they cannot be easily measured.