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Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and Bovine herpesvirus 1 is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. [1] [2] Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera with one species unassigned to a genus.
The Human alphaherpesvirus 1 virus can be classified into six clades. [2] Four of these occur in East Africa, one in East Asia and one in Europe and North America.This suggests that the virus may have originated in East Africa.
The three mammalian subfamilies – Alpha-, Beta- and Gamma-herpesviridae – arose approximately 180 to 220 mya. [16] The major sublineages within these subfamilies were probably generated before the mammalian radiation of 80 to 60 mya.
Herpes virus DNA contains a gene for a protein called ICP4, which is an important transactivator of genes associated with lytic infection in HSV-1. [47] Elements surrounding the gene for ICP4 bind a protein known as the human neuronal protein neuronal restrictive silencing factor (NRSF) or human repressor element silencing transcription factor ...
Gallid alphaherpesvirus 1 (GaHV-1) is a species of virus in the order Herpesvirales, family Herpesviridae, subfamily Alphaherpesvirinae, and genus Iltovirus. [2] Originally recognised in chickens in the United States in 1926, this virus causes avian infectious laryngotracheitis (abbreviated as AILT, ILT, or LT), a potentially fatal, economically deleterious disease, widely recognised as one of ...
Human alphaherpesvirus 2 infects humans, most often as genital herpes.In the United States more than one in six people have the virus. [3] It is primarily a sexually transmitted infection. [4]
Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children.
Bovine alphaherpesvirus 1 (BoHV-1) is a virus of the family Herpesviridae and the subfamily Alphaherpesvirinae, known to cause several diseases worldwide in cattle, including rhinotracheitis, vaginitis, balanoposthitis, abortion, conjunctivitis, and enteritis. [1]