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The genetic structure of H5N1, a highly pathogenic avian influenza virus (influenza A virus subtype H5N1), is characterized by a segmented RNA genome consisting of eight gene segments that encode for various viral proteins essential for replication, host adaptation, and immune evasion.
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [ 1 ]
Avian influenza, also known as avian flu or bird flu, is a disease caused by the influenza A virus, which primarily affects birds but can sometimes affect mammals including humans. [1] Wild aquatic birds are the primary host of the influenza A virus, which is enzootic (continually present) in many bird populations.
[8] [10] In 2020, reassortment (genetic "swapping") between these H5-2.3.4.4b viruses and other strains of avian influenza led to the emergence of a H5N1 strain with a H5-2.3.4.4b gene. [8] The virus then spread across Europe, first detected there in the autumn of 2020, before spreading to Africa and Asia. [1]
Mammalian influenza viruses tend to be labile, but can survive several hours in mucus. [57] Avian influenza virus can survive for 100 days in distilled water at room temperature, and 200 days at 17 °C (63 °F). The avian virus is inactivated more quickly in manure, but can survive for up to two weeks in feces on cages.
H5 N2 is a subtype of the species Influenzavirus A (avian influenza virus or bird flu virus). The subtype infects a wide variety of birds, including chickens, ducks, turkeys, falcons, and ostriches. Affected birds usually do not appear ill, and the disease is often mild as avian influenza viral subtypes go.
The Goose Guangdong virus refers to the strain A/Goose/Guangdong/1/96 (Gs/Gd)-like H5N1 HPAI viruses. It is a strain of the Influenzavirus A subtype H5N1 virus that was first detected in a goose in Guangdong in 1996. It is an HPAI (High Pathogenic Avian Influenza) virus, meaning that it can kill a very high percentage of chickens in a flock in ...
Avian flu virus can last indefinitely at a temperature dozens of degrees below freezing, as is found in the northernmost areas that migratory birds frequent. [citation needed] Heat kills H5N1 (i.e. inactivates the virus). Influenza A viruses can survive: Over 30 days at 0 °C (32.0 °F) (over one month at freezing temperature)