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Major depression is often associated with biomarkers indicative of inflammatory responses, with interleukin-6, interleukin-1, interleukin-2 receptor, tumor necrosis factor alpha, C-reactive protein, and monocyte chemotactic protein-1 all being found to be elevated in those with depression.
Aside from effects in the brain, the general physical risks of ECT are similar to those of brief general anesthesia. [230]: 259 Immediately following treatment, the most common adverse effects are confusion and memory loss. [227] [231] ECT is considered one of the least harmful treatment options available for severely depressed pregnant women ...
Depression is a major mental-health cause of disease burden. Its consequences further lead to significant burden in public health, including a higher risk of dementia, premature mortality arising from physical disorders, and maternal depression impacts on child growth and development. [69]
Emily Hollenbeck lived with a recurring depression she likened to a black hole, where gravity felt so strong and her limbs so heavy she could barely move. Researchers say the treatment — deep ...
In modern times, depression, more often severe cases, is more noted as an absence of pleasure, with feelings of emptiness and flatness. [4] In the United States and Canada, the costs associated with major depression are comparable to those related to heart disease, diabetes, and back problems and are greater than the costs of hypertension. [5]
The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
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