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In recent years, global health authorities have issued increasingly urgent warnings that gonorrhea has been acquiring resistance to ceftriaxone and azithromycin, with cases of highly drug ...
Each drug should be administered as a single dose, with the gentamicin entering intramuscularly at a concentration of 240 mg, along with 2 g of azithromycin taken orally. [75] If an individual is not allergic to cephalosporins but ceftriaxone is unavailable, an alternative treatment is a single dose of 800 mg cefixime consumed orally. [75]
According to a study, tinidazole used with doxycycline or azithromycin may cure NGU better than when doxycycline or azithromycin is used alone. [8] If left untreated, complications include epididymitis and infertility. Consistent and correct use of latex condoms during sexual activity greatly reduces the likelihood of infection. [9]
Gonococcemia (also known as "Disseminated gonococcal infection" [1]) is a rare complication of mucosal Neisseria gonorrhoeae infection, or Gonorrhea, that occurs when the bacteria invade the bloodstream. [2] It is characterized by fever, tender hemorrhagic pustules on the extremities or the trunk, migratory polyarthritis, and tenosynovitis. [3]
Gonorrhea is more commonly seen in males than in females and infection rates are higher in adolescents and young adults. [ 1 ] The estimated global prevalence of chlamydia, which is the most common cause of non-gonococcal urethritis, is 3.8% in women and 2.7% in men.
Gonorrhea is the second-most common sexually transmitted infection (STI) in the U.S. There were nearly 650,000 cases of gonorrhea reported in 2022, ... ceftriaxone and azithromycin, is a “global ...
Gonorrhea if left untreated may last for weeks or months with higher risks of complications. [19] One of the complications of gonorrhea is systemic dissemination resulting in skin pustules or petechia, septic arthritis, meningitis, or endocarditis. [19] This occurs in between 0.6 and 3% of infected women and 0.4 and 0.7% of infected men. [19]
The CDC recommendation is either a single oral dose (1 gram) of azithromycin, a single IM dose (250 mg) of ceftriaxone, oral (500 mg) of erythromycin three times a day for seven days, or oral (500 mg) of ciprofloxacin twice a day for three days. [9]