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The respiratory bronchioles run for considerable lengths and become increasingly alveolated with side branches of alveolar ducts that become deeply lined with alveoli. The ducts number between two and eleven from each bronchiole. [10] Each duct opens into five or six alveolar sacs into which clusters of alveoli open.
Collateral ventilation is a back-up system of alveolar ventilation that can bypass the normal route of airflow when airways are restricted or obstructed. The pathways involved include those between adjacent alveoli ( pores of Kohn ), between bronchioles and alveoli (canals of Lambert), and those between bronchioles (channels of Martin).
The lungs can be included in the lower respiratory tract or as separate entity and include the respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli. [3] Adult and pediatric airway anatomy. The respiratory tract can also be divided into a conducting zone and a respiratory zone, based on the distinction of transporting gases or ...
Ventilation–perfusion coupling is the relationship between ventilation and perfusion processes, which take place in the respiratory system and the cardiovascular system. [1] Ventilation is the movement of gas during breathing, and perfusion is the process of pulmonary blood circulation , which delivers oxygen to body tissues. [ 2 ]
Hypoventilation exists when the ratio of carbon dioxide production to alveolar ventilation increases above normal values – greater than 45mmHg. If pH is also less than 7.35 this is respiratory acidosis. Hyperventilation exists when the same ratio decreases – less than 35mmHg. If the pH is also greater than 7.45 this is respiratory alkalosis ...
High magnification photomicrograph of a lung biopsy taken showing chronic hypersensitivity pneumonitis , showing mild thickening of the walls of the small air sacs by invasion of white blood cells. A multinucleated giant cell , seen within the walls of the air sacs to the right of the picture halfway down, is an important clue to the correct ...
Alveolar pressure (PA) at end expiration is equal to atmospheric pressure (0 cm H 2 O differential pressure, at zero flow), plus or minus 2 cm H 2 O (1.5 mmHg) throughout the lung. On the other hand, gravity causes a gradient in blood pressure between the top and bottom of the lung of 20 mmHg in the erect position (roughly half of that in the ...
Alveoli are the spherical outcroppings of the respiratory bronchioles. Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by type II alveolar cells. [1] The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions.