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Solid-phase reversible immobilization, or SPRI, is a method of purifying nucleic acids from solution. It uses silica - or carboxyl -coated paramagnetic beads, which reversibly bind to nucleic acids in the presence of polyethylene glycol and a salt.
A selection of glass beads Merovingian bead Trade beads, 18th century Trade beads, 18th century. A bead is a small, decorative object that is formed in a variety of shapes and sizes of a material such as stone, bone, shell, glass, plastic, wood, or pearl and with a small hole for threading or stringing. Beads range in size from under 1 ...