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Faricimab is a 150kDa-sized bispecific antibody whose molecular structure allows a high affinity bond to both vascular endothelial growth factor A (VEGF-A) and Angiopoietin (Ang-2). [9] By blocking the action of these two growth factors, faricimab decreases migration and replication of endothelial cells allowing for stabilization of vascular ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
The FDA has approved Genentech's, a unit of Roche Holdings AG (OTC: RHHBY), Vabysmo (faricimab-svoa) for wet, or neovascular, age-related macular degeneration (AMD) and diabetic macular edema (DME).
Additional bispecific antibody drugs have since been approved by the US FDA: emicizumab, amivantamab, tebentafusp, faricimab, teclistamab, mosunetuzumab, epcoritamab, glofitamab. [31] Among the bsAb programs currently under development, the combination of CD3 and tumor surface targets are the most popular targets pairs.
Many drugs have more than one name and, therefore, the same drug may be listed more than once. Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International Nonproprietary Name
List of ibuprofen brand names; List of Icelandic brands; List of company and product names derived from Indigenous peoples; List of Italian brands; J.
List of paracetamol brand names; List of pen types, brands and companies; List of piano brand names; List of Procter & Gamble brands; List of renamed products; List of Romanian brands; List of Royal Enfield motorcycles; List of sewing machine brands; List of Slovenian brands; List of smart cards; List of toy soldiers brands; List of convertible ...
YouTubers are people mostly known for their work on the video sharing platform YouTube. The following is a list of YouTubers for whom Wikipedia has articles either under their own name or their YouTube channel name. This list excludes people who, despite having a YouTube presence, are primarily known for their work elsewhere.