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Deoxyribonuclease II (DNase II) is also known as acid deoxyribonuclease because it has optimal activity in the low pH environment of lysosomes where it is typically found in higher eukaryotes. Some forms of recombinant DNase II display a high level of activity in low pH in the absence of divalent metal ions, similar to eukaryotic DNase II. [7]
Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. [5] DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides.
Type I site-specific deoxyribonuclease (EC 3.1.21.3, type I restriction enzyme, deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent), restriction-modification system, deoxyribonuclease (adenosine triphosphate-hydrolyzing), adenosine triphosphate-dependent deoxyribonuclease, ATP-dependent DNase, type 1 site-specific deoxyribonuclease) is an enzyme. [1]
Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) is an endonuclease that hydrolyzes phosphodiester linkages of deoxyribonucleotide in native and denatured DNA, yielding products with 3'-phosphates and 5'-hydroxyl ends, which occurs as a result of single-strand cleaving mechanism. [1]
66705 Ensembl ENSG00000167968 ENSMUSG00000024136 UniProt Q92874 Q9D1G0 RefSeq (mRNA) NM_001301680 NM_001374 NM_025718 RefSeq (protein) NP_001288609 NP_001365 NP_079994 Location (UCSC) Chr 16: 2.24 – 2.24 Mb Chr 17: 24.66 – 24.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Deoxyribonuclease-1-like 2 is an enzyme that in humans is encoded by the DNASE1L2 gene. References ^ a b ...
A deoxyribonucleotide is a nucleotide that contains deoxyribose.They are the monomeric units of the informational biopolymer, deoxyribonucleic acid ().Each deoxyribonucleotide comprises three parts: a deoxyribose sugar (monosaccharide), a nitrogenous base, and one phosphoryl group. [1]
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Deoxyribonuclease gamma (also termed DNase γ, deoxyribonuclease 1L3, DNASE1L3, of deoxyribonuclease I like 3) is an enzyme that in humans is encoded by the DNASE1L3 (also termed the deoxyribonuclease 1L3 or deoxyribonuclease 1 like 3) gene.