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  2. Klinefelter syndrome - Wikipedia

    en.wikipedia.org/wiki/Klinefelter_syndrome

    This XXY chromosome arrangement is one of the most common genetic variations from the XY karyotype, occurring in approximately one in 500 live male births. [4] [13] [36] In mammals with more than one X chromosome, the genes on all but one X chromosome are not expressed; this is known as X inactivation. This happens in XXY males, as well as ...

  3. XXYY syndrome - Wikipedia

    en.wikipedia.org/wiki/XXYY_syndrome

    48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell. Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics. Females typically have two X chromosomes ...

  4. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    In most mammals, sex is determined by presence of the Y chromosome. This makes individuals with XXY and XYY karyotypes males, and individuals with X and XXX karyotypes females. [1] In the 1930s, Alfred Jost determined that the presence of testosterone was required for Wolffian duct development in the male rabbit. [6]

  5. XYY syndrome - Wikipedia

    en.wikipedia.org/wiki/XYY_syndrome

    XYY syndrome, also known as Jacobs syndrome, is an aneuploid genetic condition in which a male has an extra Y chromosome. [1] There are usually few symptoms. [2] These may include being taller than average and an increased risk of learning disabilities.

  6. XX male syndrome - Wikipedia

    en.wikipedia.org/wiki/XX_male_syndrome

    XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]

  7. Sex chromosome anomalies - Wikipedia

    en.wikipedia.org/wiki/Sex_chromosome_anomalies

    Sex chromosome anomalies belong to a group of genetic conditions that are caused or affected by the loss, damage or addition of one or both sex chromosomes (also called gonosomes). In humans this may refer to: 45, X, also known as Turner syndrome; 45,X/46,XY mosaicism, also known as X0/XY mosaicism and mixed gonadal dysgenesis; 46, XX/XY

  8. Turner syndrome - Wikipedia

    en.wikipedia.org/wiki/Turner_syndrome

    Turner syndrome (TS), commonly known as 45,X, or 45,XO, [note 1] is a chromosomal disorder in which cells have only one X chromosome or are partially missing an X chromosome (sex chromosome monosomy) leading to the complete or partial deletion of the pseudoautosomal regions (PAR1, PAR2) in the affected X chromosome.

  9. XXXYY syndrome - Wikipedia

    en.wikipedia.org/wiki/XXXYY_syndrome

    Little is known about its presentation, but associated characteristics include intellectual disability, anomalies of the external genitalia, and characteristic physical and facial features. It is not caused by characteristics of the parents, but rather occurs via nondisjunction , a random event in gamete development.