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Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
[21] [22] One of these compounds, 2,5-dimethyl-celecoxib, which entirely lacks the ability to inhibit COX-2, actually turned out to display stronger anticancer activity than celecoxib itself [23] and this anticancer effect could also be verified in highly drug-resistant tumor cells [24] and in various animal tumor models.
Amlodipine/celecoxib, sold under the brand name Consensi, is a fixed-dose combination medication used to treat both hypertension and osteoarthritis at the same time in adults. [ 1 ] [ 2 ] It contains amlodipine , as the besilate, and celecoxib . [ 1 ]
Celecoxib and rofecoxib, the first COX-2 inhibitors to reach market, were based on DuP-697. [ 5 ] [ 6 ] It took less than eight years to develop and market the first COX-2 inhibitor, with Celebrex ( celecoxib ) launched in December 1998 and Vioxx ( rofecoxib ) launched in May 1999.
Everyday painkillers, antibiotics, cancer medications, blood thinners and more are just some of the drugs that the U.S. relies on China to help manufacture China makes some of Americans’ most ...
Antidepressants, high blood pressure medication, antihistamines, and antiandrogens (medications that reduce the production of male hormone levels) are some medications that may cause ED.
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