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Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [ 2 ] such as the posterior and lateral folds of the neck , the armpits , groin , navel , forehead and other areas.
Endometrioma can potentially lead to premature ovarian failure, decreased ovarian function, or problems with ovulation. [4] Studies have also found that endometriomas occur two times more frequently in the left ovary (67%) than in the right one (33%), possibly due to the presence of the sigmoid colon on the left side. [2] [8]
Blackheads (open comedones): Blackheads are small dark brown or black spots, often on the nose and chin. They happen when pores are clogged with sebum and dead skin cells, and are open at the surface.
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.
Hyperthecosis, or ovarian hyperthecosis, is hyperplasia of the theca interna of the ovary. [1] Hyperthecosis occurs when an area of luteinization occurs along with stromal hyperplasia. The luteinized cells produce androgens , which may lead to hirsutism and virilization (or masculinization) in affected women.
In 2015 a research was done on the role of autoimmunity in premature ovarian failure. [11] In 2014 there was an ovarian autoimmune disease research that revealed at least two mechanisms that protect the ovary from an autoimmune attack. [12] Research showed that Theca cells were targeting the autoimmune deficiency within the ovary.
Schamberg's disease, (also known as "progressive pigmentary dermatosis of Schamberg", [1] "purpura pigmentosa progressiva" (PPP), [1] and "Schamberg's purpura" [1]) is a chronic discoloration of the skin found in people of all ages, usually only affecting the feet, legs or thighs or a combination.
There are many reasons why the male G-spot often remains unexplored, especially by cis, heterosexual men. For one, there’s the social script that anal sex is “gay” that many people grew up with.