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DMPA, under brand names such as Depo-Provera and Depo-SubQ Provera 104, is used in hormonal birth control as a long-lasting progestogen-only injectable contraceptive to prevent pregnancy in women. [ 38 ] [ 39 ] It is given by intramuscular or subcutaneous injection and forms a long-lasting depot , from which it is slowly released over a period ...
Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [4] – 150 mg (intramuscularly) or 104 mg (subcutaneously) every 3 months [3] Norethisterone enanthate (brand names NET EN, Noristerat, Norigest, Doryxas) [ 5 ] – 200 mg (intramuscularly) every 2 months [ 3 ]
Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. [2] It contains estradiol cypionate (EC), an estrogen, and medroxyprogesterone acetate (MPA), a progestin. [2]
(n = 16,608, with uterus, 5.2–5.6 years follow up) Estrogen alone (CEs Tooltip Conjugated estrogens 0.625 mg/day p.o.) (n = 10,739, no uterus, 6.8–7.1 years follow up) HR Tooltip Hazard ratio 95% CI Tooltip Confidence interval AR Tooltip Attributable risk HR Tooltip Hazard ratio 95% CI Tooltip Confidence interval AR Tooltip Attributable risk
Depo Provera, the shot: 4 (1 in 25) 0.2 (1 in 500) Progestogen: Injection: 12 weeks: Testosterone injection for male (unapproved, experimental method) [39] Testosterone Undecanoate: 6.1 (1 in 16) 1.1 (1 in 91) Testosterone: Intramuscular Injection: Every 4 weeks: 1999 cervical cap and spermicide (replaced by second generation in 2003) [40] FemCap
Compared to MPA, medroxyprogesterone is over two orders of magnitude less potent as a progestogen. [8] Medroxyprogesterone is also notable in that it is a minor metabolite of MPA. [ 9 ] In addition to its progestagenic activity, medroxyprogesterone is a weak antiandrogen in vitro on human androgen receptor .
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