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Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9]
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In 1811, Bernard Courtois isolated iodine from seaweed while in 1820 Jean-Francois Coindet linked iodine intake to goiter size. [5] It initially came into use as a disinfectant and a treatment for goiter. [6] [7] The following forms of iodine are found on the World Health Organization's List of Essential Medicines: [8]
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...
In gout, inflammation in joints results from the precipitation of uric acid as needle-like crystals of monosodium urate in and around synovial fluid and soft tissues of joints. [16] These crystal deposits cause inflammatory arthritis, which is initiated and sustained by mechanisms involving various proinflammatory mediators, such as cytokines. [16]
For example, rheumatoid arthritis is often treated with methotrexate and leflunomide, both of which suppresses chronic inflammation. According to the Arthritis Foundation, about 1 to 3 percent of ...