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  2. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    Multiple myeloma is the second-most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. [154] It represents about 1.8% of all new cancers and 2.1% of all cancer deaths. [7] Multiple myeloma affects slightly more men than women.

  3. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    AL amyloidosis is caused by the deposition of abnormal antibody free light chains. The abnormal light chains are produced by monoclonal plasma cells, and, although AL amyloidosis can occur without diagnosis of another disorder, it is often associated with other plasma cell disorders, such as multiple myeloma and Waldenström's macroglobulinemia. [6]

  4. Raccoon eyes - Wikipedia

    en.wikipedia.org/wiki/Raccoon_eyes

    Raccoon eyes may also be a sign of disseminated neuroblastoma, amyloidosis, Kaposi’s sarcoma or multiple myeloma. [8] It also can be temporary result of rhinoplasty. [9] Depending on cause, raccoon eyes always require urgent consultation and management, whether surgical (facial fracture or post-craniotomy) or medical (neuroblastoma or ...

  5. Lenalidomide - Wikipedia

    en.wikipedia.org/wiki/Lenalidomide

    Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone. [8] It is taken by mouth. [8]

  6. Monoclonal gammopathy - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_gammopathy

    Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia.

  7. POEMS syndrome - Wikipedia

    en.wikipedia.org/wiki/POEMS_syndrome

    Treatment of patients with this POEMS syndrome variant who have evidence of bone lesions and/or myeloma proteins are the same as those for POEMS syndrome patients. In the absence of these features, treatment with rituximab , a monoclonal antibody preparation directed against B cells bearing the CD20 antigen, or siltuximab , a monoclonal ...

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