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Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT 4 receptor agonist and indirectly as a parasympathomimetic .
Mosapride is a gastroprokinetic agent that acts as a selective 5HT 4 agonist.The major active metabolite of mosapride, known as M1, additionally acts as a 5HT 3 antagonist, [1] which accelerates emptying throughout the whole of the gastrointestinal tract in humans, [2] and is used for the treatment of gastritis, gastroesophageal reflux disease, functional dyspepsia [3] and irritable bowel ...
Cisapride (Propulsid) 2000 US Risk of fatal cardiac arrhythmias [2] Clioquinol: 1973 France, Germany, UK, US Neurotoxicity. [3] Clobutinol: 2007 Germany Ventricular arrhythmia, QT-prolongation. [14] Cloforex: 1969 Germany Cardiovascular toxicity. [3] Clomacron: 1982 UK Hepatotoxicity. [3] Clometacin: 1987 France Hepatotoxicity. [3] Co-proxamol ...
The affinity of cisapride for 5-HT 4 receptors in the heart has been implicated in the undesirable cardiac effects of cisapride itself. [ medical citation needed ] The conclusion of this study revealed that itopride is devoid of any abnormal effect on QT interval .
Compounded tirzepatide isn’t FDA-approved. This means there’s no guarantee it’s safe or effective. If you’re considering it, go to a safe source. Just because you can buy tirzepatide ...
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Semaglutide is shown to be safe over four years. Studies spanning four years show that the drug is safe, and the proven benefits may outweigh potential long-term risks. There’s no set rule for ...
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